A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

We conducted a genome-wide association study (GWAS) of pancreatic cancer in 3,851 cases and 3,934 controls drawn from twelve prospective cohort studies and eight case-control studies. Based on a logistic regression model for genotype trend effect that was adjusted for study, age, sex, self-described...

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Autors principals: Petersen, Gloria M., Amundadottir, Laufey, Fuchs, Charles S., Kraft, Peter, Stolzenberg-Solomon, Rachael Z., Jacobs, Kevin B., Arslan, Alan A., Bueno-de-Mesquita, H. Bas, Gallinger, Steven, Gross, Myron, Helzlsouer, Kathy, Holly, Elizabeth A., Jacobs, Eric J., Klein, Alison P., LaCroix, Andrea, Li, Donghui, Mandelson, Margaret T., Olson, Sara H., Risch, Harvey A., Zheng, Wei, Albanes, Demetrius, Bamlet, William R., Berg, Christine D., Boutron-Ruault, Marie-Christine, Buring, Julie E., Bracci, Paige M., Canzian, Federico, Clipp, Sandra, Cotterchio, Michelle, de Andrade, Mariza, Duell, Eric J., Gaziano, J. Michael, Giovannucci, Edward L., Goggins, Michael, Hallmans, Göran, Hankinson, Susan E., Hassan, Manal, Howard, Barbara, Hunter, David J., Hutchinson, Amy, Jenab, Mazda, Kaaks, Rudolf, Kooperberg, Charles, Krogh, Vittorio, Kurtz, Robert C., Lynch, Shannon M., McWilliams, Robert R., Mendelsohn, Julie B., Michaud, Dominique S., Parikh, Hemang, Patel, Alpa V., Peeters, Petra H.M., Rajkovic, Aleksandar, Riboli, Elio, Rodriguez, Laudina, Seminara, Daniela, Shu, Xiao-Ou, Thomas, Gilles, Tjønneland, Anne, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Van Den Eeden, Stephen K., Virtamo, Jarmo, Wactawski-Wende, Jean, Wang, Zhaoming, Wolpin, Brian M., Yu, Herbert, Yu, Kai, Zeleniuch-Jacquotte, Anne, Fraumeni, Joseph F., Hoover, Robert N., Hartge, Patricia, Chanock, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853179/
https://ncbi.nlm.nih.gov/pubmed/20101243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.522
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