Waved aCGH: to smooth or not to smooth

Array-based comparative genomic hybridization (aCGH) is a powerful tool to detect genomic imbalances in the human genome. The analysis of aCGH data sets has revealed the existence of a widespread technical artifact termed as ‘waves’, characterized by an undulating data profile along the chromosome....

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Bibliografiske detaljer
Main Authors: Leprêtre, F., Villenet, C., Quief, S., Nibourel, O., Jacquemin, C., Troussard, X., Jardin, F., Gibson, F., Kerckaert, J. P., Roumier, C., Figeac, M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853126/
https://ncbi.nlm.nih.gov/pubmed/20071741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1215
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