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Investigating the role of the Est3 protein in yeast telomere replication

The Est3 subunit of yeast telomerase, which adopts a predicted OB-fold, is essential for telomere replication. To assess the possible contributions that Est3 might make to enzyme catalysis, we compared telomerase activity from wild type and est3-Δ strains of Saccharomyces castellii, which revealed t...

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Bibliographic Details
Main Authors: Lee, Jaesung, Mandell, Edward K., Rao, Timsi, Wuttke, Deborah S., Lundblad, Victoria
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853109/
https://ncbi.nlm.nih.gov/pubmed/20047960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1173
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