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Structure of Est3 reveals a bimodal surface with differential roles in telomere replication

Telomerase is essential for continuous cellular proliferation. Substantial insights have come from studies of budding yeast telomerase, which consists of a catalytic core in association with two regulatory proteins, ever shorter telomeres 1 and 3 (Est1 and Est3). We report here a high-resolution str...

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Detalhes bibliográficos
Main Authors: Rao, Timsi, Lubin, Johnathan W., Armstrong, Geoffrey S., Tucey, Timothy M., Lundblad, Victoria, Wuttke, Deborah S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890887/
https://ncbi.nlm.nih.gov/pubmed/24344315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316453111
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