Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the Hepatitis C virus helicase

Helicases are motor proteins that are involved in DNA and RNA metabolism, replication, recombination, transcription and repair. The motors are powered by ATP binding and hydrolysis. Hepatitis C virus encodes a helicase called non-structural protein (NS3). NS3 possesses protease and helicase activiti...

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Main Authors: Matlock, Dennis L., Yeruva, Laxmi, Byrd, Alicia K., Mackintosh, Samuel G., Langston, Clint, Brown, Carrie, Cameron, Craig E., Fischer, Christopher J., Raney, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853022/
https://ncbi.nlm.nih.gov/pubmed/20108974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901977k
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