Thrombin and trypsin directly activate vagal C-fibres in mouse lung via protease-activated receptor-1

The nature of protease-activated receptors (PARs) capable of activating respiratory vagal C-fibres in the mouse was investigated. Infusing thrombin or trypsin via the trachea strongly activated vagal lung C-fibres with action potential discharge, recorded with the extracellular electrode positioned...

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Detaylı Bibliyografya
Asıl Yazarlar: Kwong, Kevin, Nassenstein, Christina, de Garavilla, Lawrence, Meeker, Sonya, Undem, Bradley J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2010
Konular:
Respiratory
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853003/
https://ncbi.nlm.nih.gov/pubmed/20142268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.181669
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