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Sphingosine‐1‐phosphate activates mouse vagal airway afferent C‐fibres via S1PR3 receptors

KEY POINTS: Sphingosine‐1‐phosphate (S1P) strongly activates mouse vagal C‐fibres in the airways. Airway‐specific nodose and jugular C‐fibre neurons express mRNA coding for the S1P receptor S1PR3. S1P activation of nodose C‐fibres is inhibited by a S1PR3 antagonist. S1P activation of nodose C‐fibres...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Patil, Mayur J., Meeker, Sonya, Bautista, Diana, Dong, Xinzhong, Undem, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441905/
https://ncbi.nlm.nih.gov/pubmed/30793318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277521
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