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Mechanism of Aldolase Control of Sorting Nexin 9 Function in Endocytosis

Sorting nexin 9 (SNX9) functions in a complex with the GTPase dynamin-2 at clathrin-coated pits, where it provokes fission of vesicles to complete endocytosis. Here the SNX9·dynamin-2 complex binds to clathrin and adapter protein complex 2 (AP-2) that line these pits, and this occurs through interac...

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Détails bibliographiques
Auteurs principaux: Rangarajan, Erumbi S., Park, HaJeung, Fortin, Emanuelle, Sygusch, Jurgen, Izard, Tina
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852936/
https://ncbi.nlm.nih.gov/pubmed/20129922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092049
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