Interaction of the Wiskott–Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells

The Wiskott–Aldrich syndrome protein (WASp) plays a major role in coupling T cell antigen receptor (TCR) stimulation to induction of actin cytoskeletal changes required for T cell activation. Here, we report that WASp inducibly binds the sorting nexin 9 (SNX9) in T cells and that WASp, SNX9, p85, an...

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Detalhes bibliográficos
Main Authors: Badour, Karen, McGavin, Mary K. H., Zhang, Jinyi, Freeman, Spencer, Vieira, Claudia, Filipp, Dominik, Julius, Michael, Mills, Gordon B., Siminovitch, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785243/
https://ncbi.nlm.nih.gov/pubmed/17242350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610543104
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