Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes

The Wiskott-Aldrich syndrome protein (WASp) has been implicated in modulation of lymphocyte activation and cytoskeletal reorganization. To address the mechanisms whereby WASp subserves such functions, we have examined WASp roles in lymphocyte development and activation using mice carrying a WAS null...

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Autors principals: Zhang, Jinyi, Shehabeldin, Amro, da Cruz, Luis A.G., Butler, Jeffrey, Somani, Ally-Khan, McGavin, Mary, Kozieradzki, Ivona, dos Santos, Antonio O., Nagy, Andras, Grinstein, Sergio, Penninger, Josef M., Siminovitch, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195687/
https://ncbi.nlm.nih.gov/pubmed/10544204
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