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Non-Invasive Optical Imaging of Staphylococcus aureus Bacterial Infection in Living Mice Using a Bis-Dipicolylamine-Zinc(II) Affinity Group Conjugated to a Near Infrared Fluorophore

Optical imaging of bacterial infection in living animals is usually conducted with genetic reporters such as light emitting enzymes or fluorescent proteins. However, there are many circumstances where genetic reporters are not applicable, and there is a need for exogenous synthetic probes that can s...

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Autors principals: Leevy, W. Matthew, Gammon, Seth T., Johnson, James R., Lampkins, Andrew J., Jiang, Hua, Marquez, Manuel, Piwnica-Worms, David, Suckow, Mark A., Smith, Bradley D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852891/
https://ncbi.nlm.nih.gov/pubmed/18260609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700376v
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