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Optical Imaging of Mammary and Prostate Tumors in Living Animals using a Synthetic Near Infrared Zinc(II)-Dipicolylamine Probe for Anionic Cell Surfaces

In vivo optical imaging shows that a fluorescent imaging probe, comprised of a near-infrared fluorophore attached to an affinity group containing two zinc(II)-dipicolylamine (Zn-DPA) units, targets prostate and mammary tumors in two different xenograft animal models. The tumor selectivity is absent...

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Detalhes bibliográficos
Main Authors: Smith, Bryan A., Akers, Walter J., Leevy, W. Matthew, Lampkins, Andrew J., Xiao, Shuzhang, Wolter, William, Suckow, Mark A., Achilefu, Samuel, Smith, Bradley D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805267/
https://ncbi.nlm.nih.gov/pubmed/20014845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908467y
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