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Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug Adriamycin: Implications for oxidative stress-mediated chemobrain

Adriamycin (ADR) is a chemotherapeutic for the treatment of solid tumors. This quinone-containing anthracycline is well known to produce large amounts of reactive oxygen species (ROS) in vivo. A common complaint of patients undergoing long-term treatment with ADR is somnolence, often referred to as...

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Detalhes bibliográficos
Main Authors: Joshi, Gururaj, Aluise, Christopher D., Cole, Marsha Paulette, Sultana, Rukhsana, Vore, Mary, St Clair, Daret K., Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852883/
https://ncbi.nlm.nih.gov/pubmed/20096337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.01.021
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