Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay

A series of phthalimide derivatives planned as drugs candidates to treat the symptoms of sickle cell anemia were evaluated in a mutagenicity test using strains of Salmonella typhimurium TA100 and TA102, without and with addition of S9 mixture, with the aim to identify the best structural requirement...

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Bibliografiske detaljer
Main Authors: dos Santos, Jean Leandro, Varanda, Eliana A., Lima, Lídia Moreira, Chin, Chung Man
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2010
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852868/
https://ncbi.nlm.nih.gov/pubmed/20386668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11020779
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