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The Tetrodotoxin Binding Site Is within the Outer Vestibule of the Sodium Channel
Tetrodotoxin and saxitoxin are small, compact asymmetrical marine toxins that block voltage-gated Na channels with high affinity and specificity. They enter the channel pore’s outer vestibule and bind to multiple residues that control permeation. Radiolabeled toxins were key contributors to channel...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Molecular Diversity Preservation International
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852835/ https://ncbi.nlm.nih.gov/pubmed/20390102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md8020219 |
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