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Structure of the dominant negative S17N mutant of Ras

The use of the dominant negative mutant of Ras has been crucial in elucidating the cellular signaling of Ras in response to the activation of various membrane-bound receptors. Although several point mutants of Ras exhibit a dominant negative effect, the asparagine to serine mutation at position 17 (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nassar, Nicolas, Singh, Kavita, Garcia-Diaz, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852684/
https://ncbi.nlm.nih.gov/pubmed/20131908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9020742
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