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Microassay for glucose-induced preproinsulin mRNA expression to assess islet functional potency for islet transplantation
BACKGROUND: The capacity for insulin synthesis in islets is important for islet transplantation to succeed. We developed a micro assay that evaluates the potency of human islets by measuring changes in glucose induced insulin gene (INS) expression using a single islet in octuplicate samples. METHODS...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852640/ https://ncbi.nlm.nih.gov/pubmed/20098276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181c4218d |
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