Role of Hydrogen Peroxide and the Impact of Glutathione Peroxidase-1 in Regulation of Cerebral Vascular Tone

Although arachidonic acid (AA) has diverse vascular effects, the mechanisms that mediate these effects are incompletely defined. The goal of the present study was to use genetic approaches to examine the role of hydrogen peroxide (H(2)O(2)), glutathione peroxidase (Gpx1, which degrades H(2)O(2)), an...

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Hauptverfasser: Modrick, Mary L., Didion, Sean P., Lynch, Cynthia M., Dayal, Sanjana, Lentz, Steven R., Faraci, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852621/
https://ncbi.nlm.nih.gov/pubmed/19352401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.37
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