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MET molecular mechanisms and therapiesin lung cancer

The MET tyrosine kinase signaling pathway is upregulated in many cancers, including lung cancer. The pathway normally promotes mitosis, cell motility and cell survival; but in cancer it can also promote cell proliferation, invasion, metastasis and angiogenesis. The activating ligand, hepatocyte grow...

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Bibliografske podrobnosti
Main Authors: Lawrence, Ryan E, Salgia, Ravi
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852571/
https://ncbi.nlm.nih.gov/pubmed/20139696
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