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MET molecular mechanisms and therapiesin lung cancer

The MET tyrosine kinase signaling pathway is upregulated in many cancers, including lung cancer. The pathway normally promotes mitosis, cell motility and cell survival; but in cancer it can also promote cell proliferation, invasion, metastasis and angiogenesis. The activating ligand, hepatocyte grow...

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Detalhes bibliográficos
Main Authors: Lawrence, Ryan E, Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852571/
https://ncbi.nlm.nih.gov/pubmed/20139696
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