Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

The negative impact of obesity on reproductive success is well documented but the stages at which development of the conceptus is compromised and the mechanisms responsible for the developmental failure still remain unclear. Recent findings suggest that mitochondria may be a contributing factor. How...

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Autors principals: Igosheva, Natalia, Abramov, Andrey Y., Poston, Lucilla, Eckert, Judith J., Fleming, Tom P., Duchen, Michael R., McConnell, Josie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852405/
https://ncbi.nlm.nih.gov/pubmed/20404917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010074
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