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Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

The negative impact of obesity on reproductive success is well documented but the stages at which development of the conceptus is compromised and the mechanisms responsible for the developmental failure still remain unclear. Recent findings suggest that mitochondria may be a contributing factor. How...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Igosheva, Natalia, Abramov, Andrey Y., Poston, Lucilla, Eckert, Judith J., Fleming, Tom P., Duchen, Michael R., McConnell, Josie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852405/
https://ncbi.nlm.nih.gov/pubmed/20404917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010074
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