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The detection of donor-directed, HLA-specific alloantibodies in recipients of unrelated hematopoietic cell transplantation is predictive of graft failure

Donor-directed human leukocyte antigen (HLA)–specific allo-antibodies (DSAs) cause graft failure in animal models of hematopoietic stem cell transplantation (HCT). Archived pretransplantation sera from graft failure patients (n = 37) and a matched case-control cohort (n = 78) were tested to evaluate...

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Autori principali: Spellman, Stephen, Bray, Robert, Rosen-Bronson, Sandra, Haagenson, Michael, Klein, John, Flesch, Susan, Vierra-Green, Cynthia, Anasetti, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852369/
https://ncbi.nlm.nih.gov/pubmed/20089963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-244525
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