ROLE OF THE HOMOLOGOUS RECOMBINATION GENES RAD51 and RAD59 IN THE RESISTANCE OF Candida albicans TO UV LIGHT, RADIOMIMETIC AND ANTI-TUMOR COMPOUNDS AND OXIDIZING AGENTS

We have cloned and characterized the RAD51 and RAD59 orthologues of the pathogenic fungus Candida albicans. CaRad51 exhibited more than 50% identity with several other eukaryotes and the conserved the catalytic domain of a bacterial RecA. As compared to the parental strain, null strains of rad51 exh...

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Hoofdauteurs: García-Prieto, Fátima, Gómez-Raja, Jonathan, Andaluz, Encarnación, Calderone, Richard, Larriba, Germán
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852118/
https://ncbi.nlm.nih.gov/pubmed/20206282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2010.02.007
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