Loss and fragmentation of chromosome 5 are major events linked to the adaptation of rad52-ΔΔ strains of Candida albicans to sorbose

C. albicans can adapt and grow on sorbose plates by losing one copy of Chr5. Since rad52 mutants of S. cerevisiae lose chromosomes at a high rate, we have investigated the ability of C. albicans rad52 to adapt to sorbose. Carad52-ΔΔ mutants generate Sou(+) strains earlier than wild type but the fina...

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Autori principali: Andaluz, Encarnación, Gómez-Raja, Jonathan, Hermosa, Belén, Ciudad, Toni, Rustchenko, E., Calderone, Richard, Larriba, Germán
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000335/
https://ncbi.nlm.nih.gov/pubmed/17300968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2007.01.005
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