HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy

Histone deacetylase (HDAC) inhibitors are emergent cancer drugs. HR23B is a candidate cancer biomarker identified in a genome-wide loss-of-function screen which influences sensitivity to HDAC inhibitors. Because HDAC inhibitors have found clinical utility in cutaneous T-cell lymphoma (CTCL), we eval...

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Detalhes bibliográficos
Main Authors: Khan, Omar, Fotheringham, Susan, Wood, Victoria, Stimson, Lindsay, Zhang, Chunlei, Pezzella, Francesco, Duvic, Madeleine, Kerr, David J., La Thangue, Nicholas B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851972/
https://ncbi.nlm.nih.gov/pubmed/20308564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913912107
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