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Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
Piccolo and bassoon are highly homologous multidomain proteins of the presynaptic cytomatrix whose function is unclear. Here, we generated piccolo knockin/knockout mice that either contain wild-type levels of mutant piccolo unable to bind Ca(2+) (knockin), ∼60% decreased levels of piccolo that is C-...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851964/ https://ncbi.nlm.nih.gov/pubmed/20332206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002307107 |
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