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Notch signaling drives IL-22 secretion in CD4(+) T cells by stimulating the aryl hydrocarbon receptor

CD4(+) helper T (Th) cells differentiate toward distinct effector cell lineages characterized by their distinct cytokine expression patterns and functions. Multiple Th cell populations secrete IL-22 that contributes to both protective and pathological inflammatory responses. Although the differentia...

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Detalhes bibliográficos
Main Authors: Alam, Muhammad Shamsul, Maekawa, Yoichi, Kitamura, Akiko, Tanigaki, Kenji, Yoshimoto, Takayuki, Kishihara, Kenji, Yasutomo, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851859/
https://ncbi.nlm.nih.gov/pubmed/20231432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911755107
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