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Total Synthesis of (±)- and (−)-Actinophyllic Acid

Development of efficient sequences for the total syntheses of (±)-actinophyllic acid (rac-1) and (−)-actinophyllic acid (1) are described. The central step in these syntheses is the aza-Cope/Mannich reaction, which constructs the previously unknown hexacyclic ring system of actinophyllic acid in one...

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Autori principali: Martin, Connor L., Overman, Larry E., Rohde, Jason M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851836/
https://ncbi.nlm.nih.gov/pubmed/20218696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100178u
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