The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro

Previous research has suggested that human herpesvirus-6 (HHV-6) may integrate into host cell chromosomes and be vertically transmitted in the germ line, but the evidence—primarily fluorescence in situ hybridization (FISH)—is indirect. We sought, first, to definitively test these two hypotheses. Per...

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Autors principals: Arbuckle, Jesse H., Medveczky, Maria M., Luka, Janos, Hadley, Stephen H., Luegmayr, Andrea, Ablashi, Dharam, Lund, Troy C., Tolar, Jakub, De Meirleir, Kenny, Montoya, Jose G., Komaroff, Anthony L., Ambros, Peter F., Medveczky, Peter G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851814/
https://ncbi.nlm.nih.gov/pubmed/20212114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913586107
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