The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro

Previous research has suggested that human herpesvirus-6 (HHV-6) may integrate into host cell chromosomes and be vertically transmitted in the germ line, but the evidence—primarily fluorescence in situ hybridization (FISH)—is indirect. We sought, first, to definitively test these two hypotheses. Per...

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Bibliografiske detaljer
Main Authors: Arbuckle, Jesse H., Medveczky, Maria M., Luka, Janos, Hadley, Stephen H., Luegmayr, Andrea, Ablashi, Dharam, Lund, Troy C., Tolar, Jakub, De Meirleir, Kenny, Montoya, Jose G., Komaroff, Anthony L., Ambros, Peter F., Medveczky, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851814/
https://ncbi.nlm.nih.gov/pubmed/20212114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913586107
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