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Quantitative theory of telomere length regulation and cellular senescence
In normal somatic cells, telomere length shortens with each cell replication. This progressive shortening is associated with cellular senescence and apoptosis. Germ cells, stem cells, and the majority of cancer cells express telomerase, an enzyme that extends telomere length and, when expressed at s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851797/ https://ncbi.nlm.nih.gov/pubmed/20207949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914502107 |
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