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Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a

A defect in the maternal copy of a ubiqutin ligase gene Ube3a can produce a neurodevelopmental defect in human children known as Angelman syndrome. We investigated the role of the maternally expressed Ube3a gene in experience-dependent development and plasticity of the mouse visual system. As demons...

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Bibliographic Details
Main Authors: Sato, Masaaki, Stryker, Michael P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851788/
https://ncbi.nlm.nih.gov/pubmed/20212164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001281107
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