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Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds
Zellweger spectrum disorder (ZSD) is a heterogeneous group of diseases with high morbidity and mortality caused by failure to assemble normal peroxisomes. There is no therapy for ZSD, but management is supportive. Nevertheless, one-half of the patients have a phenotype milder than classic Zellweger...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851769/ https://ncbi.nlm.nih.gov/pubmed/20212125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914960107 |
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