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Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds

Zellweger spectrum disorder (ZSD) is a heterogeneous group of diseases with high morbidity and mortality caused by failure to assemble normal peroxisomes. There is no therapy for ZSD, but management is supportive. Nevertheless, one-half of the patients have a phenotype milder than classic Zellweger...

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Hlavní autoři: Zhang, Rui, Chen, Li, Jiralerspong, Sarn, Snowden, Ann, Steinberg, Steven, Braverman, Nancy
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851769/
https://ncbi.nlm.nih.gov/pubmed/20212125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914960107
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