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Deoxyribonucleic Acid Damage by Monofunctional Mitomycins and Its Repair in Escherichia coli

Exposure of Escherichia coli to the antibiotic mitomycin C (MTC) at a concentration of 0.5 μg/ml caused cross-linkage between complementary strands of deoxyribonucleic acid (DNA). Derivatives of mitomycin, 7-methoxymitosene (7-MMT) and decarbamoyl mitomycin C (DCMTC), at a level as high as 20 μg/ml...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Otsuji, Nozomu, Murayama, Ichiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1972
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC285165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4550809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.109.2.475-483.1972
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