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Deoxyribonucleic Acid Damage by Monofunctional Mitomycins and Its Repair in Escherichia coli
Exposure of Escherichia coli to the antibiotic mitomycin C (MTC) at a concentration of 0.5 μg/ml caused cross-linkage between complementary strands of deoxyribonucleic acid (DNA). Derivatives of mitomycin, 7-methoxymitosene (7-MMT) and decarbamoyl mitomycin C (DCMTC), at a level as high as 20 μg/ml...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC285165/ https://ncbi.nlm.nih.gov/pubmed/4550809 |
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