Role of Phosphatidylinositol(4,5)bisphosphate Organization in Membrane Transport by the Unc104 Kinesin Motor

Unc104 (KIF1A) kinesin transports membrane vesicles along microtubules in lower and higher eukaryotes. Using an in vitro motility assay, we show that Unc104 uses a lipid binding pleckstrin homology (PH) domain to dock onto membrane cargo. Through its PH domain, Unc104 can transport phosphatidylinosi...

Full description

Saved in:
Bibliographic Details
Main Authors: Klopfenstein, Dieter R., Tomishige, Michio, Stuurman, Nico, Vale, Ronald D.
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851634/
https://ncbi.nlm.nih.gov/pubmed/12015984
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items