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Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition
Caenhorhabditis elegans Unc104 kinesin transports synaptic vesicles at rapid velocities. Unc104 is primarily monomeric in solution, but recent motility studies suggest that it may dimerize when concentrated on membranes. Using cryo-electron microscopy, we observe two conformations of microtubule-bou...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173678/ https://ncbi.nlm.nih.gov/pubmed/14638858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308020 |
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