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Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome

Smith-Lemli-Opitz syndrome (SLOS) is a recessive disease typified by 7-dehydrocholesterol (7DHC) accumulation and depletion of cholesterol. Because cholesterol is a primary component of detergent-resistant membrane domains (“rafts”), we examined the compatibility of 7DHC with raft formation. Liposom...

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Detalhes bibliográficos
Main Authors: Keller, R. Kennedy, Arnold, Thomas P., Fliesler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851617/
https://ncbi.nlm.nih.gov/pubmed/14594996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M300232-JLR200
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