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Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test case
BACKGROUND: Mathematical modeling of biological networks is an essential part of Systems Biology. Developing and using such models in order to understand gene regulatory networks is a major challenge. RESULTS: We present an algorithm that determines the smallest perturbations required for manipulati...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851584/ https://ncbi.nlm.nih.gov/pubmed/20184733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-15 |
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