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Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells

Previous studies have shown that the reduction in CD8 T cell immunity observed during high-dose influenza virus infection (IAV) is mediated via lymph node (LN) dendritic cells (DC) that express FasL and drive FasL:Fas (DC:T) induced apoptosis. However, the specific DC subset(s) within the LN and the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Langlois, Ryan A., Legge, Kevin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851488/
https://ncbi.nlm.nih.gov/pubmed/20220091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902984
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