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TLR Cross-Talk Specifically Regulates Cytokine Production by B Cells from Chronic Inflammatory Disease Patients

Chronic systemic inflammation links periodontal disease and diabetes to increased incidence of serious comorbidities. Activation of TLRs, particularly TLR2 and TLR4, promotes chronic systemic inflammation. Human B cells have been generally thought to lack these TLRs. However, recent work showed that...

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Autors principals: Jagannathan, Madhumita, Hasturk, Hatice, Liang, YanMei, Shin, Hyunjin, Hetzel, Jeremy T., Kantarci, Alpdogan, Rubin, Daniel, McDonnell, Marie E., Van Dyke, Thomas E., Ganley-Leal, Lisa M., Nikolajczyk, Barbara S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851147/
https://ncbi.nlm.nih.gov/pubmed/19917698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901517
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