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Regulation of Syk Kinase and FcRβ Expression in Human Basophils During Treatment with Omalizumab

BACKGROUND: In human basophils from different subjects, maximum IgE-mediated histamine release and the level of syk protein expression correlate well. Recent studies suggest that in some patients treated with omalizumab, the response to stimulation with anti-IgE antibody increases. In unrelated stud...

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Auteurs principaux: Zaidi, Asifa K., Saini, Sarbjit S., MacGlashan, Donald W.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850964/
https://ncbi.nlm.nih.gov/pubmed/20236696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.12.996
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