Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels

P-selectin and intercellular adhesion molecule-1 (ICAM-1) participate in inflammatory processes by promoting adhesion of leukocytes to vascular wall endothelium. Their soluble levels have been associated with adverse cardiovascular events. To identify loci affecting soluble levels of P-selectin (sP-...

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Autors principals: Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Hoogeveen, Ron C., Schnabel, Renate B., Nambi, Vijay, Bretler, Monique, Smith, Nicholas L., Peters, Annette, Lu, Chen, Tracy, Russell P., Aleksic, Nena, Heeriga, Jan, Keaney, John F., Rice, Kenneth, Lip, Gregory Y.H., Vasan, Ramachandran S., Glazer, Nicole L., Larson, Martin G., Uitterlinden, Andre G., Yamamoto, Jennifer, Durda, Peter, Haritunians, Talin, Psaty, Bruce M., Boerwinkle, Eric, Hofman, Albert, Koenig, Wolfgang, Jenny, Nancy S., Witteman, Jacqueline C., Ballantyne, Christie, Benjamin, Emelia J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Association Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850624/
https://ncbi.nlm.nih.gov/pubmed/20167578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq061
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