Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

DNA polymorphisms in a region on chromosome 5q33.1 which contains two genes, immunity related GTPase related family, M (IRGM) and zinc finger protein 300 (ZNF300), are associated with Crohn's disease (CD). The deleted allele of a 20 kb copy number variation (CNV) upstream of IRGM was recently s...

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Autors principals: Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Association Studies Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850616/
https://ncbi.nlm.nih.gov/pubmed/20106866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq041
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