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Two-Step Solid Lipid Extrusion as a Process to Modify Dissolution Behavior
Extrudates based on varying ratios of the triglyceride tripalmitin and the hydrophilic polymer polyethylene glycol as matrix formers were produced as oral dosage forms with controlled release characteristics. The extrudates were processed below the melting points of the excipients and contained the...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850486/ https://ncbi.nlm.nih.gov/pubmed/20309654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9395-y |
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