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Two-Step Solid Lipid Extrusion as a Process to Modify Dissolution Behavior

Extrudates based on varying ratios of the triglyceride tripalmitin and the hydrophilic polymer polyethylene glycol as matrix formers were produced as oral dosage forms with controlled release characteristics. The extrudates were processed below the melting points of the excipients and contained the...

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Detalles Bibliográficos
Main Authors: Windbergs, Maike, Gueres, Sinan, Strachan, Clare J., Kleinebudde, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850486/
https://ncbi.nlm.nih.gov/pubmed/20309654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9395-y
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