Mouse neuronal cells expressing exogenous bovine PRNP and simultaneous downregulation of endogenous mouse PRNP using siRNAs

Prion diseases, which are called transmissible spongiform encephalopathies (TSEs), comprise a group of fatal infectious neurodegenerative disorders. Investigation of prion strains and generation of species dependent TSE model are necessary to understand pathogenesis of the disease. To establish a BS...

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Hlavní autoři: Kang, Sang-Gyun, Roh, Yu Mi, Kang, Mi Lan, Kim, Yong-Sun, Yoo, Han Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
Short Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850418/
https://ncbi.nlm.nih.gov/pubmed/20215868
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