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Hypericin prolongs action potential duration in hippocampal neurons by acting on K(+) channels

BACKGROUND AND PURPOSE: Synaptic deficiency is generally accepted to be involved in major depression, and accordingly classic antidepressants exert their effects through enhancing synaptic efficiency. Hypericin is one of the major active constituents of extracts of St. John's Wort (Hypericum pe...

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Detalhes bibliográficos
Main Authors: Wang, Y, Shi, X, Qi, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850397/
https://ncbi.nlm.nih.gov/pubmed/20233218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00513.x
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