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Hypericin prolongs action potential duration in hippocampal neurons by acting on K(+) channels

BACKGROUND AND PURPOSE: Synaptic deficiency is generally accepted to be involved in major depression, and accordingly classic antidepressants exert their effects through enhancing synaptic efficiency. Hypericin is one of the major active constituents of extracts of St. John's Wort (Hypericum pe...

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Detalles Bibliográficos
Main Authors: Wang, Y, Shi, X, Qi, Z
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850397/
https://ncbi.nlm.nih.gov/pubmed/20233218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00513.x
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